Binaries and Visual Studio integration extension for Nemerle - high-level statically-typed programming language for the .NET platform. It offers functional, object-oriented and imperative features, has a simple C#-like syntax and a powerful meta-programming system.
The main reason is that Nemerle back-end is System.Reflection.Emit (SRE) which is not implemented in Mono as well as in .Net.
Mono runtime has specific bug which has not been fixed yet: https://bugzilla.novell.com/show_bug.cgi?id=689533
There is currently development to make replaceable back-ends.
When the work is finished, new back-end based on Common Compiler Infrastructure (CCI) will solve the problem.